Article
Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index.
Diabetes - 1 Mar 1997
Hansen T, Andersen C B, Echwald S M, Urhammer S A, Clausen J O, Vestergaard H, Owens D, Hansen L, Pedersen O
Abstract excerpt
Phosphatidylinositol 3-kinase (PI3-K) may regulate the basal plasma membrane glucose transporter recycling and the organization of the transporter intracellular pool in addition to being an insulin signal for translocation of glucose transporters to the plasma membrane. The objectives of the present study were to examine for genetic variability in the human regulatory p85alpha subunit of PI3-K, to look for an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.