Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle.

doi:10.2337/db09-1359

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Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle.

Diabetes - 1 Apr 2010

Ribel-Madsen Rasmus, Poulsen Pernille, Holmkvist Johan, Mortensen Brynjulf, Grarup Niels, Friedrichsen Martin, Jørgensen Torben, Lauritzen Torsten, Wojtaszewski Jørgen F P, Pedersen Oluf, Hansen Torben, Vaag Allan

Abstract excerpt

OBJECTIVE: Phosphoinositide 3-kinase (PI3K) is a major effector in insulin signaling. rs361072, located in the promoter of the gene (PIK3CB) for the p110beta subunit, has previously been found to be associated with homeostasis model assessment for insulin resistance (HOMA-IR) in obese subjects. T...

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PMID: 20107106
DOI: 10.2337/db09-1359
PMCID: PMC2844820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20107106-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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