Article
Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes.
BMC medical genetics - 20 Mar 2015
Hansen Tue H, Vestergaard Henrik, Jørgensen Torben, Jørgensen Marit Eika, Lauritzen Torsten, Brandslund Ivan, Christensen Cramer, Pedersen Oluf, Hansen Torben, Gjesing Anette P
Abstract excerpt
BACKGROUND: The variant rs11085226 (G) within the gene encoding polypyrimidine tract binding protein 1 (PTBP1) was reported to associate with reduced insulin release determined by an oral glucose tolerance test (OGTT) as well as an intravenous glucose tolerance test (IVGTT). The aim of the present study was to validate the association of the rs11085226 G-allele of PTBP1 with previously investigated OGTT- and...
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