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Cloning and characterization of Chinese hamster p53 cDNA.

Gene - 15 Jan 1997

Lee H, Larner J M, Hamlin J L

Abstract excerpt

We have cloned and sequenced Chinese hamster p53 cDNA and have compared the p53 sequence in different Chinese hamster cell lines to several relevant phenotypes. Our results indicate that a mutation in CHO cells that changes Thr211 to Lys211 abrogates the ability to arrest in G1 and apparently renders cells capable of amplifying DNA. However, this mutation has no effect on the G2 checkpoint or on acute...

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PMID: 9031625
DOI: 10.1016/s0378-1119(96)00592-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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