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Article

Characterization of the hamster FancG/Xrcc9 gene and mutations in CHO UV40 and NM3.

Mutagenesis - 1 May 2004

Lamerdin Jane E, Yamada Nazumi A, George James W, Souza Brian, Christian Allen T, Jones Nigel J, Thompson Larry H

Abstract excerpt

The human FANCG/XRCC9 gene, which is defective in Fanconi anemia complementation group G (FA-G) cells, was first cloned by genetic complementation of the mitomycin C (MMC) sensitivity of CHO mutant UV40. The CHO NM3 mutant was subsequently assigned to the same complementation group. The parental AA8 CHO cells are hemizygous at the FancG locus, and we identified frameshift mutations that result in N-terminal...

Read the complete abstract on PubMed

Topics

Alkylating Agents
Amino Acid Sequence
Animals
CHO Cells
Cricetinae
DNA-Binding Proteins
Fanconi Anemia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Fanconi Anemia Complementation Group G Protein

Methyl Methanesulfonate

Mitomycin

Molecular Sequence Data

Mutagens

Mutation

Source

Identifiers

PMID: 15123790
DOI: 10.1093/mutage/geh019

Genes

FANCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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