Article
Allogeneic heart transplantation activates alloreactive NK cells.
Cellular immunology - 10 Jan 1997
Petersson E, Ostraat O, Ekberg H, Hansson J, Simanaitis M, Brodin T, Dohlsten M, Hedlund G
Abstract excerpt
The ability of natural killer (NK) cells to recognize and reject transplants has so far been shown in hematopoietic grafts only. This study was designed to ascertain whether NK cells may also be involved in the rejection of transplanted organs. In most rat strain combinations, immunization with allogeneic cells induces a T cell response with cytotoxic T lymphocyte (CTL) activation. We have previously found one...
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