Article
Allograft rejection in athymic nude rats by transferred T cell subsets. II. The response of naive CD4+ and CD8+ thoracic duct lymphocytes to an isolated MHC class I disparity.
Transplantation - 1 Oct 1990
Bell E B, Rejali D, Whitby E H, Sparshott S M, Yang C P
Abstract excerpt
Athymic PVG-rnu/rnu (RT1c) rats were grafted with skin bearing isolated MHC disparities 7-14 days in advance of cell transfer. The ability of naive CD4+ or CD8+ thoracic duct lymphocytes to induce rejection was assessed by adoptive transfer of one or both T cell subsets into nude recipients beari...
Topics
- Animals
- CD4-Positive T-Lymphocytes
- Cytotoxicity, Immunologic
- Graft Rejection
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Phenotype
- Rats
- Rats, Nude
- Skin Transplantation
- T-Lymphocytes, Regulatory
- Transplantation, Homologous