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Article

Application of a dicistronic mRNA expression vector to antisense RNA expression in mammalian cells.

Antisense & nucleic acid drug development - 1 Jan 1996

Yamauchi Y, Kobayashi M, Tanaka A

Abstract excerpt

One important role of antisense RNA expression in mammalian cell biology is to partially suppress the functions of target genes of which the functions are unknown but which are indispensable for host cell growth. Therefore, we applied a dicistronic mRNA expression vector to express antisense p53 RNA in mouse fibrosarcoma MethA cells. We also established several clones in which the p53 gene functions were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9012867
DOI: 10.1089/oli.1.1996.6.305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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