Article
Single nucleotide polymorphisms in the regulatory regions of the HLA-DRB-expressed genes.
Human immunology - 1 Mar 2005
Fan Xinlan, Lan Dongming, Lin Bin, Xie Yi, Liu Zehuan, Zhen Guoqing, Fu Yonggui, Xu Anlong
Abstract excerpt
DRB genes encode proteins that play an important role in the immune response, and their expressional regulation is crucial to the immune reaction. Sequence variation at the regulatory region can directly affect the gene expression level. The aim of the present study was to use Chinese samples to investigate the variation in the regulation region of the human leukocyte antigen (HLA)-DRB-expressed genes. Seventy-...
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