Article
Apoptotic activity of REAPER is distinct from signaling by the tumor necrosis factor receptor 1 death domain.
The Journal of biological chemistry - 18 Oct 1996
Chen P, Lee P, Otto L, Abrams J
Abstract excerpt
REAPER (RPR) is a 65-amino acid protein that is critical activator of programmed cell death in Drosophila. On the basis of sequence alignment data, it was recently proposed that RPR might represent an ancestral molecule from which the death domain in a number of proteins may have evolved. We test...
Topics
- Adaptor Proteins, Signal Transducing
- Amino Acid Sequence
- Animals
- Antigens, CD
- Apoptosis
- Carrier Proteins
- Drosophila
- Drosophila Proteins
- Fas-Associated Death Domain Protein
- Flow Cytometry
- Molecular Sequence Data
- Peptides
- Phenotype
- Receptors, Tumor Necrosis Factor
- Receptors, Tumor Necrosis Factor, Type I
- Sequence Alignment
- Signal Transduction
- Transfection