Article
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death.
Cell - 29 Dec 1995
Hay B A, Wassarman D A, Rubin G M
Abstract excerpt
Apoptotic cell death is a mechanism by which organisms eliminate superfluous or harmful cells. Expression of the cell death regulatory protein REAPER (RPR) in the developing Drosophila eye results in a small eye owing to excess cell death. We show that mutations in thread (th) are dominant enhanc...
Topics
- Amino Acid Sequence
- Animals
- Apoptosis
- Biological Evolution
- Chromosome Deletion
- Drosophila
- Drosophila Proteins
- Enhancer Elements, Genetic
- Eye
- Genes, Insect
- Genetic Testing
- Humans
- Inhibitor of Apoptosis Proteins
- Insect Proteins
- Mammals
- Microscopy, Electron, Scanning
- Molecular Sequence Data
- Mutation