Cell surface phenotype and increased penetration of human multidrug-resistant ovarian carcinoma cells into in vitro collagen-fibroblasts matrix.

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Article

Cell surface phenotype and increased penetration of human multidrug-resistant ovarian carcinoma cells into in vitro collagen-fibroblasts matrix.

Neoplasma - 1 Jan 1996

Sedlák J, Sedláková O, Hlavcák P, Hunáková L, Bízik J, Grófová M, Chorváth B

Abstract excerpt

Human multidrug resistant ovarian carcinoma cells (A2780/ADR) exhibited increased in vitro penetration into the collagen-normal human fibroblasts matrix, increased cell surface expression of alpha 6 integrin (CD49f antigen) and slightly increased expression of alpha 2 (CD49b) integrin compared wi...

Topics

Antibodies, Monoclonal
Antigens, CD
Drug Resistance, Neoplasm
Female
Fibroblasts
Flow Cytometry
Humans
Membrane Proteins
Metalloendopeptidases
Neoplasm Invasiveness
Ovarian Neoplasms
Phenotype
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8996563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8996563-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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