Article
[Laminin and its alpha 6 integrin receptor in the regulation of human hepatocellular carcinoma cell phenotypes].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jan 2003
Lu Tian-jing, Zhang Qing-yun, Zhou Rou-li
Abstract excerpt
OBJECTIVE: To study the role of integrin alpha 6 in cell attachment, spread, survival/proliferation and differentiation of human hepatocellular carcinoma (HCC) BEL-7402 cells on various substrates by monoclonal antibody against the extracellular domain of alpha 6 subunit (IA6ED McAb). METHODS: The effect of McAb on attachment and spread of BEL-7402 cells on LN or FN substrate was examined. MTT analysis was used...
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