Article
Integrin expression in human melanoma cells with differing invasive and metastatic properties.
Clinical & experimental metastasis - 1 Mar 1992
Gehlsen K R, Davis G E, Sriramarao P
Abstract excerpt
During the process of tumor cell invasion and metastasis, tumor cells are known to interact with extracellular matrix proteins, endothelial cells, platelets and other organ-specific structures. Integrins are cell surface molecules which mediate cell-matrix and cell-cell interactions and are likely to be important for tumor cell survival and dissemination. The purpose of this study was to characterize the integrin...
Topics
- Cell Adhesion
- Culture Media
- Humans
- Integrins
- Melanoma
- Microbial Collagenase
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Neoplasm Seeding
- Phenotype
- Precipitin Tests