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Article

Membrane gangliosides and immuno-mediated cytolysis in drug sensitive and treatment-induced multidrug resistant human ovarian cancer cells.

Anticancer research - 1 Jan 2000

Mazzoni A, Trave F, Fabbri M, Leto G, Ghidoni R

Abstract excerpt

The pattern of cytoplasmic membrane gangliosides and two cellular features which have been reported to be related to the expression of different membrane gangliosides, namely adhesion to solid substrates and susceptibility to the lytic activity of immune effector cells, have been investigated in drug sensitive A2780 human ovarian cancer cells and in two treatment-induced multidrug resistant sublines (A2780-DX1...

Topics

Antineoplastic Agents
Cell Adhesion
Doxorubicin
Drug Resistance
Female
Gangliosides
Humans
Killer Cells, Lymphokine-Activated
Lymphocytes
Membrane Proteins
Neoplasm Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovarian Neoplasms

Phenotype

Tumor Cells, Cultured

Source

Identifiers

PMID: 1776860

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1776860-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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