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Article

Altered adhesion properties and alpha v integrin expression in a cisplatin‐resistant human ovarian carcinoma cell line

13 Dec 2001

Abstract excerpt

In order to elucidate the mechanisms underlying the development of chemoresistance in ovarian cancer, we have previously established the IGROV1-R10 cisplatin-resistant cell line by mimicking a clinical protocol of drug administration on IGROV1 human ovarian carcinoma cells. Both IGROV1 and IGROV1-R10 cells were able to grow as a monolayer and to release cell clusters into the medium. However, IGROV1-R10 cells...

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PMID: 11774263
DOI: 10.1002/ijc.1600

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