Article
p53 gene mutation in relation to p53 protein accumulation in male and female breast cancer.
Neoplasma - 1 Jan 1996
Nayak B K, Baral R N, Das B R
Abstract excerpt
The aim of this investigation was to study the prevalence of p53 gene mutations in male and female breast cancers and to find out the relationship between this event and p53 protein expression. Genomic p53 was amplified by polymerase chain reaction (PCR). Exons 5-8 were screened for mutations using single stranded conformation polymorphism (SSCP) analysis. P53 protein expression was detected by...
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