p53 gene mutation in relation to p53 protein accumulation in male and female breast cancer.

Article

p53 gene mutation in relation to p53 protein accumulation in male and female breast cancer.

Neoplasma - 1 Jan 1996

Nayak B K, Baral R N, Das B R

Abstract excerpt

The aim of this investigation was to study the prevalence of p53 gene mutations in male and female breast cancers and to find out the relationship between this event and p53 protein expression. Genomic p53 was amplified by polymerase chain reaction (PCR). Exons 5-8 were screened for mutations usi...

Topics

Breast Neoplasms
Breast Neoplasms, Male
DNA, Neoplasm
Female
Genes, p53
Humans
Immunohistochemistry
Male
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Tumor Suppressor Protein p53

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