Article
The effect of immunohistochemically detected p53 accumulation in prognosis of breast cancer; A retrospective survey of outcome.
PloS one - 1 Jan 2017
Sadighi Sanambar, Zokaasadi Mohammad, Kasaeian Amir, Maghsudi Somaye, Jahanzad Issa, Kamranzadeh Fumani Hosein
Abstract excerpt
BACKGROUND: P53; a tumor suppressor gene has known to have a role in a group of human cancers. Its role in breast cancer; one of the most prevalent malignancies worldwide, is still controversial. The current study is designed to evaluate the prognostic role of p53 mutation in breast cancer. METHODS: one hundred and eighty five breast cancer patients were studied in this retrospective study. P53 mutation was...
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