Article
p53 gene alteration and protein expression in Iranian women with infiltrative ductal breast carcinoma.
Cancer letters - 10 Aug 2001
Pezeshki A M, Farjadian S, Talei A, Vasei M, Gharesi-Fard B, Doroudchi M, Ghaderi A
Abstract excerpt
Genetic alterations in the p53 tumor suppressor gene with or without protein overexpression have been reported to be associated with sporadic breast cancer. To assess the role of p53 in infiltrative ductal breast carcinoma among Iranian patients, p53 protein expression and p53 gene mutations were studied by immunohistochemical analysis and single-strand conformation polymorphism, respectively. The p53 protein was...
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