Article
p53 overexpression in squamous cell carcinoma of the esophagus.
Annals of surgical oncology - 1 Jan 1997
Baron P L, Gates C E, Reed C E, Dikeman R L, Drosieko J J, Passmore R N, Bromberg J S, Willingham M C
Abstract excerpt
BACKGROUND: Coastal South Carolina has a high incidence of squamous cell carcinoma of the esophagus (SCCE) among black residents. Overexpression and mutations of the p53 tumor suppressor gene have been noted in SCCE from other high-incidence regions. The purpose of this study was to determine the frequency of p53 overexpression in this region both in patients with SCCE and in normal subjects. METHODS: Normal and...
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