Article
P53 overexpression in epidermoid carcinoma of the head and neck.
Sao Paulo medical journal = Revista paulista de medicina - 1 Jan 2000
Logullo A F, Kowalski L P, Nonogaki S, Miguel R E, Torloni H, Brentani R R
Abstract excerpt
UNLABELLED: The theory of field cancerization in tumors of the head and neck reflects the complex oncogenesis that occurs in this region. The mechanisms that control cell proliferation at the molecular level in epidermoid carcinomas (ECs) of the upper aerodigestive tract are still unclear. Mutations in p53 are the genetic alterations most often detected in ECs of the head and neck and seem to contribute actively...
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