Article
Prevalence of p53 mutations and protein expression in esophageal cancers in southern Thailand.
International journal of cancer - 3 Jul 1997
Suwiwat S, Oda H, Shimizu Y, Ishikawa T
Abstract excerpt
To investigate p53 alterations in esophageal squamous-cell carcinomas of patients in the high-risk area of southern Thailand, 72 paraffin-embedded samples were analyzed immunohistochemically for p53 protein expression and 16 frozen samples for p53 mutational status. Forty-two of the 72 tumors (58.3%) showed p53 protein accumulation in the nuclei of tumor cells. Expression of p53 in tumors was not significantly...
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