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Article

Prevalence of hepatitis B virus precore stop codon mutations in chronically infected children.

World journal of gastroenterology - 14 Apr 2006

Wintermeyer Philip, Gerner Patrick, Gehring Stephan, Karimi Afshin, Wirth Stefan

Abstract excerpt

AIM: To find out whether there is a significant difference in the prevalence of the precore stop codon mutation between HBeAg positive and anti-HBe positive children. METHODS: We investigated a large pediatric population of 155 European children (mean age 10.9 years) with chronic hepatitis B by PCR and direct sequencing. Ninety were HBeAg positive and 65 had seroconversion to anti-HBe. Additionally genotyping was...

Topics

Alanine Transaminase
Child
Codon, Terminator
Cross-Sectional Studies
Hepatitis B Core Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16610027
DOI: 10.3748/wjg.v12.i14.2235
PMCID: PMC4087652

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