Article
Prevalence of hepatitis B virus precore stop codon mutations in chronically infected children.
World journal of gastroenterology - 14 Apr 2006
Wintermeyer Philip, Gerner Patrick, Gehring Stephan, Karimi Afshin, Wirth Stefan
Abstract excerpt
AIM: To find out whether there is a significant difference in the prevalence of the precore stop codon mutation between HBeAg positive and anti-HBe positive children. METHODS: We investigated a large pediatric population of 155 European children (mean age 10.9 years) with chronic hepatitis B by PCR and direct sequencing. Ninety were HBeAg positive and 65 had seroconversion to anti-HBe. Additionally genotyping was...
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