Article
Low prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis type B in France.
Journal of hepatology - 1 Apr 1993
Féray C, Gigou M, Samuel D, Bernuau J, Bismuth H, Bréchot C
Abstract excerpt
The presence of mutants of the precore region of the hepatitis B virus genome was investigated in French patients with fulminant hepatitis. Only one of the 10 subjects had a detectable mutation by direct sequencing. On the other hand, 2/10 and 3/10 had evidence of coinfection by hepatitis D virus and hepatitis C virus. These results indicate that the precore stop mutation at codon 28 is not a general condition in...
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