Low prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis type B in France.

doi:10.1016/s0168-8278(05)80019-4

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Article

Low prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis type B in France.

Journal of hepatology - 1 Apr 1993

Féray C, Gigou M, Samuel D, Bernuau J, Bismuth H, Bréchot C

Abstract excerpt

The presence of mutants of the precore region of the hepatitis B virus genome was investigated in French patients with fulminant hepatitis. Only one of the 10 subjects had a detectable mutation by direct sequencing. On the other hand, 2/10 and 3/10 had evidence of coinfection by hepatitis D virus and hepatitis C virus. These results indicate that the precore stop mutation at codon 28 is not a general condition in...

Topics

Adult
Base Sequence
DNA, Viral
Female
France
Hepatic Encephalopathy
Hepatitis B
Hepatitis B virus
Humans
Liver Transplantation
Male
Molecular Sequence Data
Mutation
Prevalence
Retrospective Studies

Source

Open in PubMed

Identifiers

PMID: 8340604
DOI: 10.1016/s0168-8278(05)80019-4

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