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Article

Fractional allele loss data indicate distinct genetic populations in the development of non-small-cell lung cancer.

British journal of cancer - 1 Dec 1996

Field J K, Neville E M, Stewart M P, Swift A, Liloglou T, Risk J M, Ross H, Gosney J R, Donnelly R J

Abstract excerpt

Allelic imbalance or loss of heterozygosity (LOH) has been widely used to assess genetic instability in tumours, and high LOH on chromosome arms 3p, 9p and 17p has been considered to be a common event in non-small-cell lung cancer (NSCLC). We have investigated allelic imbalance in 45 NSCLCs using 92 microsatellite markers on 38 chromosome arms. LOH of 38% was observed on 3p using nine markers, 58% on 9p using 15...

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Source

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Identifiers

PMID: 8980398
DOI: 10.1038/bjc.1996.661
PMCID: PMC2074832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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