Article
A transgene-induced mitotic arrest mutation in the mouse allelic with Oligosyndactylism.
Genetics - 1 Dec 1996
Pravtcheva D D, Wise T L
Abstract excerpt
Oligosyndactylism (Os) is a radiation-induced mutation on mouse chromosome 8 associated with early postimplantation lethality in homozygotes and abnormal development of the limbs and kidneys in heterozygotes. The recessive lethal effect of Os is due to a mitotic block of the embryonic cells that...
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