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Article

Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant t(w73) to 200 kb.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2001

Zwart R, Verhaagh S, de Jong J, Lyon M, Barlow D P

Abstract excerpt

Here we report an analysis of two candidate genes for the t(w73) implantation mutation. The t(w73) gene maps to a 20-cM region of mouse Chromosome (Chr) 17 known as the t-complex, which exists in a wild-type and t haplotype form in present-day mice. The t haplotype variants contain several mutant alleles affecting male fertility and embryonic viability and offer the opportunity to identify genes critical for...

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PMID: 11641723
DOI: 10.1007/s00335-001-3016-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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