Article
Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila.
Development (Cambridge, England) - 1 May 1990
Gridley T, Gray D A, Orr-Weaver T, Soriano P, Barton D E, Francke U, Jaenisch R
Abstract excerpt
The Mov 34 mutation is a recessive embryonic lethal mutation caused by retroviral integration in the murine germline. This integration disrupts a transcription unit that appears to encode a novel protein. The Mov 34 proviral integration is located on mouse chromosome 8 and the human homolog of this gene has been mapped to chromosome region 16q23-q24. An evolutionarily conserved syntenic relationship exists...
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