Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of Apc10/Doc1 in three alleles of oligosyndactylism.

Genomics - 15 Feb 2001

Pravtcheva D D, Wise T L

Abstract excerpt

Oligosyndactylism (Os) is a radiation-induced mouse mutation associated with recessive lethality and a dominant effect on limb and kidney development. The lethal effect of the mutation is due to a cell-autonomous block in the transition from metaphase to anaphase. We have previously characterized two transgene-induced mutations, 94-A and 94-K, which are allelic with Os. These mutations facilitated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Chromosomes, Artificial, Bacterial
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Saccharomyces cerevisiae Proteins

Share to Sequence Deletion

Share to Sequence Homology, Nucleic Acid

Share to Transgenes

Source

Identifiers

PMID: 11247669
DOI: 10.1006/geno.2001.6474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Disruption of Apc10/Doc1 in three alleles of oligosyndactylism.PMID 11247669Read ↗

A transgene-induced mitotic arrest mutation in the mouse allelic with Oligosyndactylism.Semantic proximity Read ↗

Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila.Semantic proximity Read ↗

Characterization of the Apc10/Doc1 subunit of the anaphase promoting complex in Drosophila melanogaster.Semantic proximity Read ↗

The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm.Semantic proximity Read ↗

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.Semantic proximity Read ↗

Targeted disruption of Col11a2 produces a mild cartilage phenotype in transgenic mice: comparison with the human disorder otospondylomegaepiphyseal dysplasia (OSMED).Semantic proximity Read ↗

Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1.Semantic proximity Read ↗

Omi, a recessive mutation on chromosome 10, is a novel allele of Ostm1.Semantic proximity Read ↗

Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.