Article
Disruption of Apc10/Doc1 in three alleles of oligosyndactylism.
Genomics - 15 Feb 2001
Pravtcheva D D, Wise T L
Abstract excerpt
Oligosyndactylism (Os) is a radiation-induced mouse mutation associated with recessive lethality and a dominant effect on limb and kidney development. The lethal effect of the mutation is due to a cell-autonomous block in the transition from metaphase to anaphase. We have previously characterized...
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