Article
Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
The Journal of experimental medicine - 1 Dec 1996
Reid S W, McAdam S, Smith K J, Klenerman P, O'Callaghan C A, Harlos K, Jakobsen B K, McMichael A J, Bell J I, Stuart D I, Jones E Y
Abstract excerpt
In the cellular immune response, recognition by CTL-TCRs of viral antigens presented as peptides by HLA class I molecules, triggers destruction of the virally infected cell (Townsend, A.R.M., J. Rothbard, F.M. Gotch, G. Bahadur, D. Wraith, and A.J. McMichael. 1986. Cell. 44:959-968). Altered pept...
Topics
- Amino Acid Sequence
- Cell Line
- Clone Cells
- Computer Graphics
- Crystallography, X-Ray
- Gene Products, gag
- Genetic Variation
- HIV-1
- HLA-B8 Antigen
- Humans
- Immunity, Cellular
- Peptide Fragments
- Protein Conformation
- Protein Structure, Secondary
- T-Lymphocytes, Cytotoxic