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Article

A unique unresponsive CD4+ T cell phenotype post TCR antagonism.

Cellular immunology - 1 Jan 2010

Edwards Lindsay J, Evavold Brian D

Abstract excerpt

The functional outcomes of the T cell's interaction with the peptide:MHC complex can be dramatically altered by the introduction of a single amino acid substitution. Previous studies have described the varied effects of these altered peptide ligands (APL) on T cell responses. These outcomes of T cell interaction with an APL include the induction of clonal unresponsiveness (anergy) and inhibition of T cell...

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Identifiers

PMID: 20031121
DOI: 10.1016/j.cellimm.2009.11.002
PMCID: PMC2838172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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