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Article

Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma

25 Nov 1999

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Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 10597307
DOI: 10.1038/sj.onc.1203192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinomaPMID 10597307Read ↗

Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19Semantic proximity Read ↗

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumourSemantic proximity Read ↗

Biallelic expression of the H19 and IGF2 genes in hepatocellular carcinomaSemantic proximity Read ↗

H19 lncRNA: Roles in tumorigenesis.Semantic proximity Read ↗

High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19.Semantic proximity Read ↗

IGF2 but not H19 shows loss of imprinting in human glioma.Semantic proximity Read ↗

Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma.Semantic proximity Read ↗

Aberrant DNA Methylation of IGF2-H19 Locus in Human Fetus and in Spermatozoa From Assisted Reproductive TechnologiesSemantic proximity Read ↗

Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors.Semantic proximity Read ↗

Imprinting and expression of insulin-like growth factor-II and H19 in normal breast tissue and breast tumor.Semantic proximity Read ↗

Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a ‘passkey’ to cancerogenesisSemantic proximity Read ↗

Alterations in expression of imprinted genes from the H19/IGF2 loci in a multigenerational model of intrauterine growth restriction (IUGR)Semantic proximity Read ↗

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