Article
Dissociation of IGF2 and H19 imprinting in human brain.
Brain research - 9 Nov 1998
Pham N V, Nguyen M T, Hu J F, Vu T H, Hoffman A R
Abstract excerpt
The human IGF2 and H19 genes are imprinted in most normal tissues. Alterations of genomic imprinting or loss of imprinting (LOI) have been observed in a number of malignant tumors. Although LOI has been linked to tumorigenesis, loss of IGF2 imprinting has also been observed in choroid plexus and...
Topics
- Aging
- Alleles
- Brain Chemistry
- DNA
- DNA Primers
- Female
- Gene Expression Regulation, Developmental
- Humans
- Insulin-Like Growth Factor II
- Pregnancy
- Promoter Regions, Genetic
- RNA
- Tissue Distribution