Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians.

doi:10.1016/s0026-0495(98)90250-5

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Article

Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians.

Metabolism: clinical and experimental - 1 May 1998

Nagi D K, Foy C A, Mohamed-Ali V, Yudkin J S, Grant P J, Knowler W C

Abstract excerpt

In Caucasian subjects, an insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is associated with coronary artery disease (CAD) and fatal myocardial infarction. The underlying mechanism(s) of this association is not fully understood. Pima Indians have a low incide...

Topics

Adult
Blood Glucose
Coronary Disease
Data Interpretation, Statistical
Electrocardiography
Female
Genes
Genotype
Humans
Hypertension
Indians, North American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin

Insulin Resistance

Male

Metabolic Diseases

Middle Aged

Peptidyl-Dipeptidase A

Plasminogen Activator Inhibitor 1

Source

Open in PubMed

Identifiers

PMID: 9591757
DOI: 10.1016/s0026-0495(98)90250-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9591757-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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