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Article

PAI-1 4G/5G insertion/deletion promoter polymorphism and microvascular complications in type 2 diabetes mellitus.

Wiener klinische Wochenschrift - 1 Oct 2005

Funk Marion, Endler Georg, Exner Markus, Marculescu Rodrig, Endler Lukas, Abrahamian Heidemarie, Mauler Harald, Grimm Angelika, Raith Marianne, Mannhalter Christine, Prager Rudolf, Irsigler Karl, Wagner Oswald F

Abstract excerpt

BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) plays an important role in the regulation of fibrinolysis and extracellular matrix turnover. PAI-1 4G/5G insertion/deletion polymorphism in the PAI-1 promoter region has been shown to modulate PAI-1 plasma levels. We investigated the relationship between this polymorphism and the prevalence of diabetic nephropathy and retinopathy in patients with type 2...

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PMID: 16416371
DOI: 10.1007/s00508-005-0425-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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