Diabetic retinopathy, promoter (4G/5G) polymorphism of PAI-1 gene, and PAI-1 activity in Pima Indians with type 2 diabetes.

doi:10.2337/diacare.20.8.1304

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Article

Diabetic retinopathy, promoter (4G/5G) polymorphism of PAI-1 gene, and PAI-1 activity in Pima Indians with type 2 diabetes.

Diabetes care - 1 Aug 1997

Nagi D K, McCormack L J, Mohamed-Ali V, Yudkin J S, Knowler W C, Grant P J

Abstract excerpt

OBJECTIVE: To examine the relationship between plasma plasminogen activator inhibitor 1 (PAI-1) activity and PAI-1 gene (4G/5G) polymorphism and diabetic retinopathy in Pima Indians with type 2 diabetes. RESEARCH DESIGN AND METHODS: We studied 171 Pima Indians with type 2 diabetes between the age...

Topics

Adult
Aged
Arizona
Blood Glucose
DNA
DNA Primers
Diabetes Mellitus, Type 2
Diabetic Retinopathy
Female
Genotype
Humans
Indians, North American
Longitudinal Studies
Male
Middle Aged
Plasminogen Activator Inhibitor 1
Polymerase Chain Reaction
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 9250459
DOI: 10.2337/diacare.20.8.1304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9250459-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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