Article
Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics.
Neuroscience letters - 27 Feb 1998
Ohmori O, Shinkai T, Kojima H, Terao T, Suzuki T, Mita T, Abe K
Abstract excerpt
Catechol-O-methyltransferase (COMT) is an enzyme which inactivates catecholamine neurotransmitters by methylation, and is considered a candidate for involvement in schizophrenia. A functional COMT gene polymorphism influencing the enzyme activities, the high activity (val-108) and the low activit...
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