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Article

Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 May 2006

Burgess Robert W, Jucius Thomas J, Ackerman Susan L

Abstract excerpt

Netrin signaling is important to guide migrating neurons and axons in many systems. Experiments with vertebrate CNS explants suggested netrin is bifunctional, attracting some axons and repelling others. Netrin1-expressing cells attracted spinal commissural axons and repelled trochlear cranial nerve axons in these experiments. Subsequent genetic studies demonstrated that multiple axon types, including those of the...

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Identifiers

PMID: 16723533
DOI: 10.1523/JNEUROSCI.0736-06.2006
PMCID: PMC6675264

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DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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