Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms of ephrin receptor protein kinase-independent signaling in amphid axon guidance in Caenorhabditis elegans.

Genetics - 1 Nov 2013

Grossman Emily N, Giurumescu Claudiu A, Chisholm Andrew D

Abstract excerpt

Eph receptors and their ephrin ligands are key conserved regulators of axon guidance and can function in a variety of signaling modes. Here we analyze the genetic and cellular requirements for Eph signaling in a Caenorhabditis elegans axon guidance choice point, the ventral guidance of axons in the amphid commissure. The C. elegans Eph receptor EFN-1 has both kinase-dependent and kinase-independent roles in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Axons
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Helminth

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins c-abl

Share to Receptor Protein-Tyrosine Kinases

Share to Sense Organs

Source

Open in PubMed Open full text

Identifiers

PMID: 23979582
DOI: 10.1534/genetics.113.154393
PMCID: PMC3813872

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms of ephrin receptor protein kinase-independent signaling in amphid axon guidance in Caenorhabditis elegans.PMID 23979582Read ↗

Multiple ephrins control cell organization in C. elegans using kinase-dependent and -independent functions of the VAB-1 Eph receptor.Semantic proximity Read ↗

Characterization of loss-of-function and gain-of-function Eph receptor tyrosine kinase signaling in C. elegans axon targeting and cell migration.Semantic proximity Read ↗

The divergent C. elegans ephrin EFN-4 functions inembryonic morphogenesis in a pathway independent of the VAB-1 Eph receptor.Semantic proximity Read ↗

The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans.Semantic proximity Read ↗

The Caenorhabditis elegans Ephrin EFN-4 Functions Non-cell Autonomously with Heparan Sulfate Proteoglycans to Promote Axon Outgrowth and Branching.Semantic proximity Read ↗

A novel Eph receptor-interacting IgSF protein provides C. elegans motoneurons with midline guidepost function.Semantic proximity Read ↗

The <i>C. elegans</i> ephrin EFN-4 functions non-cell autonomously with heparan sulfate proteoglycans to promote axon outgrowth and branchingSemantic proximity Read ↗

Drosophila Eph receptor guides specific axon branches of mushroom body neurons.Semantic proximity Read ↗

AST-1, a novel ETS-box transcription factor, controls axon guidance and pharynx development in C. elegans.Semantic proximity Read ↗

Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts.Semantic proximity Read ↗

The C. elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis.Semantic proximity Read ↗

Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.