Article
Regulation of cathepsin D dependent on the phenotype of colon carcinoma cells.
International journal of cancer - 15 Nov 1996
Hennebicq Reig S, Kim I, Janin A, Grard G, Hémon B, Moreau O, Porchet N, Aubert J P, Degand P, Huet G
Abstract excerpt
We have studied the intracellular trafficking of cathepsin D in different colon carcinoma cell populations: the HT-29 cell line, composed of >95% undifferentiated cells; 2 subpopulations derived from this cell line, containing cells committed to differentiation into mucin-secreting cells (HT-29 MTX) or enterocyte-like cells (HT-29 G-) after confluence; and the Caco-2 cell line, which spontaneously differentiates...
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