Article
Cell surface phenotype and cytokine secretion in Caco-2 cell cultures: increased RANTES production and IL-2 transcription upon stimulation with IL-1beta.
Tissue & cell - 1 Dec 2001
Rodriguez-Juan C, Pérez-Blas M, Valeri A P, Aguilera N, Arnaiz-Villena A, Pacheco-Castro A, Martin-Villa J M
Abstract excerpt
Caco-2 is a colonic tumour cell line which, when cultured, spontaneously exhibits enterocyte-like characteristics. Given the difficulties in maintaining long-lasting cultures of enterocytes, this cell line may be a suitable in vitro model to carry out experiments trying to delineate the involvement of enterocytes in local immune responses, and their role in pathology. It seems then reasonable to obtain a detailed...
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