Article
Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance.
Journal of cellular physiology - 1 Aug 1994
Ho S B, Yan P S, Dahiya R, Neuschwander-Tetri B A, Basbaum C, Kim Y S
Abstract excerpt
Colorectal cancers are often composed of cell types representing various differentiated cell lineages, however little is known concerning the relationship of differentiation and drug resistance in these cancers. The present study was performed to develop and characterize a stable, differentiated...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Adenocarcinoma
- Aminopeptidases
- Animals
- Antigens, Neoplasm
- Butyrates
- Butyric Acid
- Carrier Proteins
- Cell Differentiation
- Cell Division
- Colonic Neoplasms
- Doxorubicin
- Drug Resistance
- Glutathione
- Glutathione Transferase
- Humans
- Membrane Glycoproteins
- Mice
