Article
Mucin production by colon cancer cells cultured in serum-free medium.
International journal of cancer - 11 Nov 1991
Real F X, Egea G, Francí C, Schüssler M H, Xu M, Welt S
Abstract excerpt
Although many colon cancer cell lines are available for study, few of them exhibit differentiated properties. When cultured in medium containing fetal bovine serum, WiDr cells (WiDr-FBS) show an undifferentiated phenotype: growth as a multilayer of cells adherent to plastic and lack of polarization, brush border, and mucin vacuoles. In contrast, WiDr cells cultured in a chemically-defined serum-free medium...
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