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Article

Induced differentiation in HT29, a human colon adenocarcinoma cell line

15 Aug 1999

Abstract excerpt

The human colon adenocarcinoma cell line HT29 displays an undifferentiated phenotype under standard growth conditions. When these cells were cultured for 21 days and then treated with forskolin, most of the cells formed brush borders on their apical surfaces. Brush border formation was inhibited by cytochalasin D but not by colchicine. Colchicine, nocodazole and taxol were found to induce differentiation and...

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PMID: 10413674
DOI: 10.1242/jcs.112.16.2657

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