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Article

Expression of D-type cyclins in colon cancer and in cell lines from colon carcinomas

12 Jul 2005

Abstract excerpt

Cyclins D1, D2 and D3 play important roles in cell proliferation and differentiation. Although their abnormal expression has been linked to cancer development and progression in a number of tissues, the expression of cyclin D2 and D3 proteins in colon cancer has not yet been characterised. In this study, we examined cyclin D1, D2 and D3 protein expression by Western blot analysis in tumour and adjacent normal...

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PMID: 16012517
DOI: 10.1038/sj.bjc.6602709

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