Article
Caco-2 cells express a combination of colonocyte and enterocyte phenotypes.
Journal of cellular physiology - 1 Mar 1998
Engle M J, Goetz G S, Alpers D H
Abstract excerpt
Caco-2 cells are derived from a human colonic adenocarcinoma, but differentiate into small intestinal-like cells after confluence. While this enterocytic differentiation has been well studied, the presumed parallel loss of colonocyte function has not been as thoroughly examined. To follow the phenotype for both tissues, Western blots were performed using antisera recognizing liver/bone/kidney alkaline phosphatase...
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