Article
TP53 alterations in atypical ductal hyperplasia and ductal carcinoma in situ of the breast.
Breast cancer research and treatment - 1 Jan 1996
Chitemerere M, Andersen T I, Holm R, Karlsen F, Børresen A L, Nesland J M
Abstract excerpt
Abnormalities in the TP53 tumour suppressor gene in 75 atypical ductal hyperplasias and 62 ductalcarcinomas in situ (DCIS) of the breast were studied using immunohistochemistry and mutation analysis. Accumulation of p53 protein was detected in 10 out of 62 (16%) DCIS, whereas no cases of positive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
