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Article

TP53 alterations in atypical ductal hyperplasia and ductal carcinoma in situ of the breast.

Breast cancer research and treatment - 1 Jan 1996

Chitemerere M, Andersen T I, Holm R, Karlsen F, Børresen A L, Nesland J M

Abstract excerpt

Abnormalities in the TP53 tumour suppressor gene in 75 atypical ductal hyperplasias and 62 ductalcarcinomas in situ (DCIS) of the breast were studied using immunohistochemistry and mutation analysis. Accumulation of p53 protein was detected in 10 out of 62 (16%) DCIS, whereas no cases of positive staining was observed in the atypical lesions. TP53 mutations were identified in four out of 30 (13%) DCIS by constant...

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Source

Identifiers

PMID: 8944328
DOI: 10.1007/BF01807155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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