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Article

Relationship between abnormal p53 protein and failure to express p21 protein in human breast carcinomas.

The Journal of pathology - 1 Feb 1997

Bukholm I K, Nesland J M, Kåresen R, Jacobsen U, Børresen A L

Abstract excerpt

Alterations in the p53 protein are a common feature in most malignancies, including breast carcinomas. p53 protein alterations contribute to malignant transformation in several ways, through genomic instability and accumulation of additional genetic alterations in other genes, through alteration of the p53-dependent apoptotic pathway, and through downregulation of downstream effector proteins such as p21...

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PMID: 9120716
DOI: 10.1002/(SICI)1096-9896(199702)181:2<140::AID-PATH745>3.0.CO;2-A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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