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Article

Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse.

Nature genetics - 1 Dec 1996

Fijneman R J, de Vries S S, Jansen R C, Demant P

Abstract excerpt

Many complex traits, including susceptibility to lung cancer, are controlled by multiple genes--quantitative trait loci (QTLs). We facilitated the mapping of QTLs by making use of recombinant congenic strains (RCS), a system of mouse inbred strains in which the genetic complexity is reduced, and by applying MQM-mapping (multiple-QTL models or marker-QTL-marker), a multilocus method with an increased power of...

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PMID: 8944028
DOI: 10.1038/ng1296-465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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