Article
Genetics of quantitative and qualitative aspects of lung tumorigenesis in the mouse: multiple interacting Susceptibility to lung cancer (Sluc) genes with large effects.
Experimental lung research - 1 Jan 2000
Fijneman R J, van der Valk M A, Demant P
Abstract excerpt
Inbred strains of mice exhibit large differences in their susceptibility to various complex quantitative genetic traits, among which is the susceptibility to lung cancer. These differences are caused by the combined effects of multiple quantitative trait loci (QTLs). Due to their multiplicity, it...
Topics
- Adenoma
- Animals
- Carcinogens
- Chromosome Mapping
- Crosses, Genetic
- DNA, Neoplasm
- Ethylnitrosourea
- Female
- Genetic Linkage
- Genetic Predisposition to Disease
- Lung Neoplasms
- Maternal-Fetal Exchange
- Mice
- Mice, Inbred A
- Multigene Family
- Pregnancy
- Quantitative Trait, Heritable
- Recombination, Genetic